Pharmacogenetics – Level 3

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Pharmacogenetics – Level 3

This lesson will provide an overview of pharmacogenetics and its importance in medical practice.

Syllabus

1. Advanced Course: Pharmacogenomics in Clinical Practice

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This advanced course is designed for healthcare professionals interested in integrating pharmacogenomics (PGx) into their clinical practice. The course will cover various topics, including PGx billing, informed shared decision-making, ethical and legal considerations, laboratory and implementation considerations, informatics and clinical decision support design, genomic literacy, learning experiences incorporating PGx, precepting a PGx project, and an overview of PGx databases. The course will provide healthcare professionals with practical knowledge and skills to implement PGx testing in their clinical practice effectively.

Course format

The course will be delivered in a hybrid format, with online modules and live virtual sessions. The course will include case-based learning and interactive discussions to facilitate peer-to-peer learning and engagement.

Course requirements

Participants should have a basic understanding of pharmacology and genetics. Access to a computer and internet connection is required to participate in the course. Participants will be required to complete online modules and attend live virtual sessions. A certificate of completion will be awarded to participants who complete the course requirements.

Course Outline

PGx Billing

  1. Overview of PGx billing codes
  2. Commercial billing considerations
  3. Federal billing considerations
  4. Direct pay options
  5. Institution-specific considerations (e.g., Provider-Based Billing)

PGx Informed Shared Decision Making/Informed Consent; Patient Consultation Pearls

  1. Pre-test consultation and counseling
  2. Post-test consultation and counseling
  3. Strategies for engaging patients in informed, shared decision making

Ethical/Legal/Social Implications

  1. Overview of the Genetic Information Nondiscrimination Act (GINA)
  2. State law protections
  3. Secondary findings and their implications for patients

Laboratory Considerations

  1. Overview of PGx laboratory technologies
  2. Selection of a reference lab for PGx testing
  3. Quality control and assurance in PGx testing

Implementation Considerations

  1. Planning for PGx implementation
  2. Identifying knowledge and logistic barriers and solutions
  3. Evidence-based approaches to implementing PGx testing in clinical practice

Informatics/Clinical Decision Support Design and considerations

  1. Location of alerts in electronic medical records (EMRs)
  2. Designing effective alerts and decision support tools
  3. Approaches for integrating PGx information into clinical workflows

Genomic Literacy

  1. Overview of genomic literacy for healthcare providers, pharmacists, and patients
  2. Strategies for educating patients and healthcare professionals about PGx

Overview of PGX Databases

  1. Overview of FDA labeling for PGx drugs
  2. Overview of PGx databases, including CPIC, PharmGKB, OncoKB, and others
  3. Strategies for using PGx databases to inform clinical decision making

2. Advanced Course: Real-world examples of pharmacogenetic testing

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3. Advanced Course: Case studies involving pharmacogenetic testing

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4. Advanced Course: Pharmacogenetics in Clinical Practice

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5. Advanced Course: Implementing pharmacogenomics (PGx)

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6. Advanced Course: Introduction: Pharmacogenetic testing is an essential tool

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7. Advanced Course: PGx testing participant guide

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8. Advanced Course: Participant manual for the PGx

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